Lectins: Proteins That Interpret the Sugar Code
نویسندگان
چکیده
منابع مشابه
Lectins: getting familiar with translators of the sugar code.
The view on the significance of the presence of glycans in glycoconjugates is undergoing a paradigmatic change. Initially mostly considered to be rather inert and passive, the concept of the sugar code identifies glycans as highly versatile platform to store information. Their chemical properties endow carbohydrates to form oligomers with unsurpassed structural variability. Owing to their capac...
متن کاملEukaryotic Glycosylation and Lectins: Hardware of the Sugar Code (Glycocode) in Biological Information Transfer
Introduction Biomolecules with capacity to form oligoor polymers can be likened to letters of an alphabet making up words and messages in sentences. To succeed as hardware in information storage the molecular letters must be sufficiently different to minimize the risk potential for ambiguities. Also, high-density coding capacity is beneficial for keeping the size of code units small. Further fa...
متن کاملLectins as Carbohydrate-binding Proteins
Lectins are cell-binding and agglutinating (glyco)proteins found in a variety of living forms. They will be defined here as homogeneous carbohydrate-binding (glyco)proteins principally of plant (seed) origin but also occurring in invertebrate (and vertebrate?) forms. In recent years, lectins have been employed in studying a wide range of biological phenomena including cell differentiation and m...
متن کاملLectins: Proteins with Diverse Applications
Article history: Received on: 12/04/2013 Revised on: 23/04/2013 Accepted on: 04/05/2013 Available online: 12/05/2013 Lectins are proteins that bind to carbohydrates and sugar containing substances in a specific and reversible way or precipitate glycoconjugates. These heterogeneous class of carbohydrate-binding proteins or glycoproteins of non-immune origin are capable of specific recognition of...
متن کاملDiverse sugar-binding specificities of marine invertebrate C-type lectins.
The sugar-binding specificities of C-type lectins isolated from marine invertebrates were investigated by frontal affinity chromatography (FAC) using 100 oligosaccharides. The lectins included BRA-2 and BRA-3, multiple lectins from the hemolymph of the acorn barnacle, Megabalanus rosa, and BRL from the acorn barnacle, Balanus rostatus. The diverse sugar-binding specificities of the C-type lecti...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2003
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac031373w